Carisoprodol (trade names embody Soma, Somadril, Carisoma, Carisoprodol Watson, Listaflex, Somacid, Vanadom) is a muscle relaxant from carbamic acid esters pharmacological group. This medication is indicated together with rest and physical therapy to alleviate musculoskeletal pain, skeletal muscle spasms, stiffness, muscle injuries, pressure, sprain, acute again pain, discomfort associated with short-term, painful musculoskeletal situations, and for different medical functions. It is also extensively off-label used as recreational drug. Carisoprodol may be prescribed alone for monotherapy or in combinations with other medicine, such as psycholeptics.
Clinical presentation </h2
Overdosage of Carisoprodol (Soma) tablets commonly produces CNS melancholy. Death, coma, respiratory melancholy, hypotension, seizures, delirium, hallucinations, dystonic reactions, nystagmus, blurred imaginative and prescient, mydriasis, euphoria, muscular incoordination, rigidity, and/or headache have been reported with Soma overdosage. Serotonin syndrome has been reported with carisoprodol intoxication. Many of the carisoprodol overdoses have occurred in the setting of a quantity of drug overdoses (including medication of abuse, illegal medicine, and alcohol). The effects of an overdose of this treatment and other CNS depressants (e.g., alcohol, benzodiazepines, opioids, tricyclic antidepressants) can be additive even when one of the medicine has been taken in the recommended dosage. Fatal unintended and non-accidental overdoses of SOMA have been reported alone or in combination with CNS depressants.
Treatment of overdosage
Basic life help measures must be instituted as dictated by the medical presentation of the Soma overdose. Vomiting shouldn’t be induced due to the danger of CNS and respiratory depression, and subsequent aspiration. Circulatory help ought to be administered with volume infusion and vasopressor brokers if wanted. Seizures must be handled with intravenous benzodiazepines and the reoccurrence of seizures may be handled with phenobarbital. In instances of extreme CNS depression, airway protective reflexes may be compromised and tracheal intubation should be thought-about for airway safety and respiratory assist.
For decontamination in circumstances of extreme toxicity, activated charcoal ought to be considered in a hospital setting in patients with large overdoses who present early and aren’t demonstrating CNS despair and might shield their airway.